People Are Dying Because of Medicinal Reactions Adverse Drug Reactions

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People Are Dying Because of Medicinal Reactions Adverse Drug Reactions

People Are Dying Because of Medicinal Reactions
People Are Dying Because of Medicinal Reactions


In a world where medical advancements have saved countless lives, it is sobering to acknowledge that people are still losing their lives due to medicinal reactions. This crisis transcends borders, affecting individuals in both affluent and impoverished nations alike. Let us delve into the heart of this issue and explore the urgent need for change.

The High Price of Medicines: A Global Problem (People Are Dying Because of Medicinal Reactions Adverse Drug Reactions)

Access to life-saving drugs is a fundamental human right. However, the exorbitant cost of medications remains a significant barrier. Consider these alarming examples:

  1. Kadcyla: In the United Kingdom, the National Health Service grapples with the decision not to pay for Kadcyla, a breakthrough medicine for breast cancer. Its staggering price tag of £102,405 (almost four times the UK’s 2014 per capita income) denies patients access to a potentially life-extending treatment1.
  2. Hepatitis C Treatment: In France, the cost of providing medicines to treat all Hepatitis C patients would exceed the annual budget of public hospitals in Paris. These life-saving treatments can cost over $100,000 per patient1.
  3. Neglected Diseases: Investment in research and development (R&D) for diseases affecting impoverished populations remains inadequate. Profit-driven models discourage pharmaceutical companies from focusing on diseases that won’t yield substantial financial gains. Consequently, when crises like Ebola strike, we find ourselves unprepared, lacking vaccines, diagnostics, and treatments1.


The Silent Toll: Bad Reactions to Medication in India(People Are Dying Because of Medicinal Reactions)

Adverse drug reactions (ADRs), though often silent, cast a long shadow over the lives of countless individuals in India. These unintended and harmful responses to medications pose a significant threat to patient safety and well-being. Let us delve into the complexities of this issue and explore the urgent need for vigilance

Rethinking the System

It is time for a paradigm shift. We must:

  • Prioritize Access: Access to medicines should be universal, irrespective of economic status or geographic location.
  • Challenge Intellectual Property Rules: The current system, driven by pharmaceutical industry interests, clashes with the human right to health. We need a fair balance that ensures innovation without sacrificing accessibility.
  • Invest in R&D for Neglected Diseases: Our collective well-being demands research into neglected diseases. The current antimicrobial resistance crisis underscores this urgency1.

As we mourn those lost to medicinal reactions, let us channel our grief into action. Lives depend on it.

FAQs on Indian Government’s Proposal for Bridge Course for Ayush Doctors(People Are Dying Because of Medicinal Reactions)

Q: What is the Indian Government proposing regarding Ayush doctors and modern medicine?

A: The Indian Government is considering implementing a one-year bridge course for Ayush (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) doctors, allowing them to practice modern medicine.

Q: Is modern medicine practice risk-free?

A: No, modern medicine practice carries inherent risks, including medical errors, hospital-acquired infections, multi-drug resistance, and surgical complications. Medical errors and adverse drug events are significant contributors to morbidity and mortality globally, underscoring the need for rigorous training and oversight in healthcare.

Q: What steps can be taken to prevent adverse events in modern medicine practice?

A: Increasing awareness, monitoring, and improving record-keeping can help prevent adverse events in modern medicine practice. Additionally, patients should be educated about potential side effects of medications, and healthcare professionals should promptly address any adverse reactions reported by patients.

Q: How prevalent are adverse events and adverse drug reactions in India?

A: In India, adverse events are responsible for millions of injuries and deaths each year. Adverse drug reactions and adverse events contribute significantly to hospitalizations and mortality, highlighting the importance of patient safety measures in healthcare delivery.

Frequently Asked Questions (FAQs) on Adverse Drug Reactions India (ADRs) and Pharmacovigilance in India(People Are Dying Because of Medicinal Reactions)

reporting adverse drug:- council for international organization medical science


  1. What is an adverse drug reaction (ADR)?
    • An adverse drug reaction (ADR) refers to any harmful or unintended reaction to a medication, which occurs at doses normally used for treatment. These reactions can range from mild to severe and can occur immediately after taking the medication or after prolonged use.
  2. What is the significance of reporting adverse drug reactions?
    • Reporting adverse drug reactions is crucial as it provides regulatory authorities with valuable data to make informed decisions regarding drug safety and usage. It helps identify potential risks associated with medications and can lead to necessary regulatory actions such as withdrawal from the market, label warnings, or dosage adjustments.
  3. What challenges does India face in reporting adverse drug reactions?
    • India faces several challenges in reporting adverse drug reactions effectively. These challenges include:
      • Low awareness and reporting culture among healthcare professionals.
      • Lack of mandatory reporting requirements for doctors.
      • Insufficient knowledge among healthcare professionals regarding the importance of reporting ADRs and how to recognize them.
      • Dependence on unqualified practitioners and pharmacies for healthcare access in certain regions.
      • Limited resources and infrastructure for pharmacovigilance activities.
  4. What are the consequences of underreporting adverse drug reactions?
    • Underreporting of adverse drug reactions can have significant consequences, including:
      • Delayed identification of potentially harmful medications.
      • Continued use of medications with serious side effects, leading to increased patient harm.
      • Lack of data-driven regulatory actions to address unsafe medications.
  5. How can healthcare professionals contribute to improving ADR reporting in India?
    • Healthcare professionals play a vital role in improving ADR reporting by:
      • Increasing awareness about the importance of reporting ADRs among peers and colleagues.
      • Actively monitoring patients for signs of adverse drug reactions and promptly reporting them to the appropriate authorities.
      • Participating in pharmacovigilance training programs to enhance knowledge and skills related to ADR recognition and reporting.
  6. What regulatory actions can be taken based on reported adverse drug reactions?
    • Regulatory actions based on reported adverse drug reactions may include:
      • Withdrawal of medications from the market.
      • Label warnings or dosage adjustments to mitigate risks.
      • Restrictions on the use of medications in specific populations or conditions.
      • Requirement for additional safety data or post-marketing surveillance.
  7. What role does pharmacovigilance play in ensuring medication safety?
    • Pharmacovigilance plays a crucial role in monitoring the safety of medications throughout their lifecycle. It involves the systematic collection, assessment, and reporting of adverse drug reactions to facilitate early detection of safety concerns and minimize patient harm.
  8. How can patients contribute to pharmacovigilance efforts?
    • Patients can contribute to pharmacovigilance efforts by:
      • Reporting any unusual or unexpected reactions to their healthcare providers.
      • Participating in patient education programs to increase awareness about medication safety.
      • Utilizing pharmacovigilance reporting systems or hotlines to report adverse drug reactions directly to regulatory authorities.
  9. What measures can be taken to address the underreporting of adverse drug reactions in India?
    • Addressing the underreporting of adverse drug reactions in India requires a multi-faceted approach, including:
      • Implementing mandatory reporting requirements for healthcare professionals.
      • Enhancing pharmacovigilance training and education initiatives.
      • Strengthening infrastructure and resources for pharmacovigilance activities.
      • Encouraging collaboration between healthcare providers, regulatory authorities, and pharmaceutical companies to improve reporting mechanisms.
  10. What are the potential risks of medication use with slow-onset adverse effects?
    • Medications with slow-onset adverse effects, such as vitamin deficiencies or long-term complications, pose unique risks to patients. These risks may include:
      • Delayed recognition of adverse effects, leading to prolonged exposure to harmful medications.
      • Exacerbation of underlying health conditions or development of new complications over time.
      • Increased healthcare utilization and costs associated with managing long-term adverse effects.
      • Compromised patient outcomes and quality of life if adverse effects go undetected or untreated.

This FAQ aims to provide insights into the challenges, consequences, and potential solutions related to adverse drug reactions and pharmacovigilance in India, emphasizing the importance of proactive reporting and collaborative efforts to ensure medication safety and improve patient outcomes.

Modern medicine, while undoubtedly life-saving and transformative, also carries inherent risks of medical errors, adverse events, and adverse drug reactions. In India, the scale of these risks is significant, with approximately 5.2 million injuries recorded each year due to medical errors and adverse events. These injuries stem from various sources, including mishaps from medications, hospital-acquired infections, and complications such as blood clots that develop in the legs due to immobilization during hospital stays.

According to data from the Harvard School of Public Health, India experiences a loss of approximately 3 million healthy life years annually due to these injuries, underscoring the profound impact of healthcare-related adverse events on public health.

Comparing hospitalization rates, for every 100 hospitalizations, there are approximately 14.2 adverse events in high-income countries and 12.7 in low- and middle-income countries, indicating a widespread challenge in healthcare safety and quality across different economic contexts.

In the United States, adverse events contribute to a staggering 180,000 deaths annually, with adverse drug events ranking as the fourth most common cause of death, resulting in over 100,000 deaths per year. Extrapolating these figures to India, it is estimated that there are approximately 400,000 deaths annually due to adverse drug reactions, along with 720,000 adverse events.

The incidence of serious adverse drug reactions in India stands at 6.7%, with fatal adverse drug reactions accounting for 0.32% of cases. Adverse events occur at a rate of 4%, with deaths attributed to adverse events comprising 14% of adverse events. Notably, adverse drug events contribute to extended hospital stays, with an average prolongation of two days.

In India, 6% of visits to medical emergency departments are drug-related, with adverse drug reactions alone accounting for 45% of all adverse events. These statistics underscore the need for robust patient safety measures, rigorous monitoring of medication use, and continuous efforts to enhance healthcare quality and prevent adverse events in medical practice.


Adverse Drug Reactions: A Major Cause of Deaths Highlighted by Recent Study

reporting adverse drug :- counclie of internatonal organizations of medical science


A recent study published in the Journal of the American Medical Association has brought attention to the alarming rate at which adverse drug reactions contribute to fatalities in hospitals. The study, conducted by researchers from the University of Toronto, has shed light on the significant impact of adverse drug reactions on mortality rates in both Sweden and the United States.

According to the findings of the study, adverse drug reactions account for approximately 3% of deaths in Sweden, emphasizing the global magnitude of the issue. However, the statistics are even more concerning in the United States, where more than 100,000 individuals lose their lives annually due to adverse reactions to medication. These reactions make drug-related fatalities one of the leading causes of death in the country.

The study underscores that these deaths are not a result of medical errors in prescribing or administering drugs, but rather a consequence of the inherent risks associated with pharmaceuticals. Virtually all medications have the potential to cause adverse side effects in certain individuals, even when taken at appropriate doses.

Dr. Bruce Pomeranz, a professor of neuroscience at the University of Toronto and one of the authors of the study, emphasized the need to increase awareness of the toxic components of drugs. He highlighted that adverse drug reactions often go unrecognized, with many deaths attributed to other causes on death certificates, without acknowledging the role of medications.

The study, which combined the results of 39 smaller studies through meta-analysis, revealed a staggering number of deaths attributed to adverse drug reactions. While some experts have raised concerns about the methodology and potential overestimation of the figures, they acknowledge the seriousness of the problem.

Dr. Lucian Leape, a professor of health policy at the Harvard School of Public Health, emphasized that adverse drug reactions in india remain a significant issue, regardless of the exact numbers. He commended the study for drawing attention to the problem and advocating for increased awareness and monitoring.

Despite the alarming statistics, experts stress that medications play a crucial role in healthcare and save millions of lives each year. Dr. Michael A. Friedman of the Food and Drug Administration emphasized the importance of respecting medications while acknowledging their potential side effects.

While efforts to prevent adverse drug reactions in india are ongoing, including increased awareness, monitoring, and improved record-keeping, patients are urged not to discontinue medications without consulting healthcare professionals. The benefits of medication generally outweigh the risks, but patients should remain vigilant and report any adverse reactions promptly.

As researchers continue to explore ways to mitigate the risks associated with medications, the study serves as a reminder of the importance of careful medication management and ongoing efforts to improve patient safety in healthcare settings.


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